Taking naltrexone an hour before drinking prevents these endorphins from creating the pleasurable “buzz” that reinforces habitual drinking. If a participant eventually chooses total abstinence, they may continue naltrexone daily to remove any potential desire for alcohol. The route depends on personal values, physical health, and the trajectory of progress. Secure a Physician’s Guidance– Find a doctor aware of TSM or open to MAT. Doesn’t Address All Underlying TriggersWhile TSM can block biochemical cravings, it doesn’t automatically resolve emotional trauma, social triggers, or environmental pressures fueling alcohol misuse. No Suitability for EveryoneIndividuals with severe comorbidities, advanced liver disease, or active opioid analgesic usage may not be good candidates for TSM.

Other Medications to Stop Drinking
- So, even if we consume alcohol, the rewarding effects are diminished or entirely absent because naltrexone is blocking our brain’s access points.
- She was able to enjoy social gatherings without the compulsion to drink excessively.
- Connect with an expert coach, get your medication consult referral, and access our private community with tools and support to start your moderate drinking journey.
Rethink Drink is dedicated to revolutionising the approach to alcohol recovery through The Sinclair Method (TSM). As a leading resource in the field, Rethink Drink provides insightful articles, inspiring stories, and expert advice to help individuals regain control over their relationship with alcohol. Our mission is to educate, support, and empower those affected by alcohol dependency, offering a compassionate and science-backed solution to achieve sustainable recovery. Through our blog and podcast, we share valuable content from certified coaches, healthcare professionals, and individuals who have successfully transformed their lives using TSM. Join us on a journey of transformation and discover how you can rethink drink and reclaim a healthier, happier life. In general, the Sinclair Method is a good option for those who are committed to making alcoholism treatment changes to their alcohol use.
- At its core, The Sinclair Method is based on the principle of pharmacological extinction.
- The Sinclair Method, like all recovery methods, requires effort and work.
- This is largely because it neglects to address the mental toll that alcoholism can have on a person.
- Changing drinking habits takes time, and we’re here with a judgment-free community, personalized support, and specialized resources always at your fingertips.
- The Sinclair Method is an individualized treatment approach to help people reduce or even quit drinking.
Understanding The Sinclair Method (TSM) for Alcoholism

This theory proposes that naltrexone blocks the reaction of the opioid system to alcohol-related cues. A 2014 brain-imaging study by Mann et al. seems to confirm that naltrexone blocks cravings induced by alcohol-related cues. However, it is currently impossible to know whether this drop in craving was due to the effect of naltrexone, to a placebo effect, or simply to the effect of time. A randomized placebo-controlled trial is needed to determine whether there is actually a medication effect when naltrexone is taken while abstaining. Still, this study showed that naltrexone plus abstinence does not lead to increased craving, as author Roy Eskapa had claimed it would.
Learn More About Medication for Problem Drinking
Naltrexone was previously prescribed by physicians and told patients to take it every day and to totally abstain from alcohol. This method is not effective as it does not allow the extinction process to take place. Extinction only works if the alcoholic takes the pill and continues to drink. We highly recommend that all TSM patients work with an addiction counselor as they work towards sobriety. We have also had some patients whose addiction was primarily biochemical that were able to reduce their drinking without extensive counseling or therapy.
- While the Sinclair Method primarily focuses on pharmacological intervention through naltrexone, integrating behavioral therapy can significantly enhance its effectiveness.
- You’ll meet millions of fellow Reframers in our 24/7 Forum chat and daily Zoom check-in meetings.
- Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

For more information about Suboxone (buprenorphine/naloxone) see Suboxone.com, the full Prescribing Information, and Medication Guide, or talk to your healthcare provider. Most inpatient treatment centers follow a traditional model of abstinence-based treatment, and won’t administer a moderation-based treatment. The Sinclair Method is more often supported in outpatient settings Sinclair method like medical offices. Workit Health offers naltrexone treatment utilizing The Sinclair Method for alcohol addiction in the states where we offer Workit Clinic. If you aren’t in one of these states, you can refer to the C Three Foundation’s directory of in-person and telehealth naltrexone providers.